Aptiom has possible interactions with some other drugs. Examples include statins and birth control pills. Talk with your doctor to avoid potentially harmful effects from Aptiom interactions.
Aptiom is prescribed for partial-onset seizures (also called focal seizures) in adults and children ages 4 years and older.
An interaction occurs when one substance causes another substance to have a different effect than expected.
The active ingredient in Aptiom is called eslicarbazepine. The medication comes as an oral tablet.
By learning about possible Aptiom interactions, you can work with your doctor to ensure Aptiom will be safe and effective for you to take.
To learn about Aptiom’s interactions, keep reading. For additional information about Aptiom, including details about its uses, see this Aptiom overview article.
Before you start treatment with Aptiom, tell your doctor and pharmacist about any prescription, over-the-counter, and other medications you take. By sharing this information with them, you may help prevent possible interactions.
To learn whether Aptiom interacts with supplements, herbs, or vitamins, see the “Aptiom and other interactions” section.
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Here’s a table of drugs that can interact with Aptiom. Keep in mind this table doesn’t include all drugs that may interact with Aptiom. Some of these interactions are described in detail in “Drug interactions in depth.”
Drug class or drug name | Drug examples | Interaction result with Aptiom |
birth control pills | • desogestrel/ethinyl estradiol (Enskyce, Kariva) • drospirenone/ethinyl estradiol (Loryna, Yaz) • ethinyl estradiol/norethindrone (Junel, Balziva) | can make birth control pills less effective |
certain other seizure medications | • carbamazepine (Tegretol, others) • phenobarbital (Sezaby) • phenytoin (Dilantin, Phenytek) • primidone (Mysoline) | can make Aptiom less effective |
certain statins | • atorvastatin (Lipitor) • lovastatin (Altoprev) • simvastatin (Zocor) | can make certain statins less effective |
certain HIV medications | • atazanavir (Reyataz) • cobicistat (Tybost) • darunavir (Prezista) | can make certain HIV medications less effective |
proton pump inhibitors | • esomeprazole (Nexium) • lansoprazole (Prevacid) • omeprazole (Prilosec) | may increase risk of side effects from proton pump inhibitors or make proton pump inhibitors less effective |
certain cancer drugs | • abemaciclib (Verzenios) • brigatinib (Alunbrig) • entrectinib (Rozlytrek) | can make certain cancer drugs less effective |
certain migraine drugs | • atogepant (Qulipta) • rimegepant (Nurtec ODT) | can make certain migraine drugs less effective |
certain antidepressants | • citalopram (Celexa) • sertraline (Zoloft) • venlafaxine (Effexor XR) | can increase the risk of low sodium levels |
diuretics | • bumetanide (Bumex) • furosemide (Lasix) • hydrochlorothiazide (Microzide) | can increase the risk of low sodium levels |
clarithromycin | – | can make clarithromycin less effective |
Sometimes, certain factors or conditions could prevent your doctor from prescribing Aptiom due to the risk of harm. These are known as contraindications.
The contraindications of Aptiom include:
Having had an allergic reaction to Aptiom or any of its ingredients
If you’ve had an allergic reaction to Aptiom or any of its ingredients or to a similar drug called oxcarbazepine (Trileptal), your doctor will likely not prescribe Aptiom. Taking the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.
Note:Before you start treatment with Aptiom, it’s important to tell your doctor if this contraindication applies to you. They can determine whether to prescribe Aptiom.
There are no known interactions between Aptiom and alcohol. However, if you drink alcohol, your doctor may advise you to avoid or limit it during Aptiom treatment.
This is because drinking alcohol while taking the drug may worsen some of Aptiom side effects. For example, you may experience:
- nausea
- vomiting
- headache
- sleepiness
- dizziness
- problems with balance or coordination
- blurry vision
In addition, consuming large amounts of alcohol can cause liver damage. Aptiom may also cause liver damage as a side effect. This means that drinking alcohol during Aptiom treatment may increase the risk of liver problems.
If you consume alcohol during Aptiom treatment, these side effects may be more likely to occur. If you have questions about drinking alcohol while taking Aptiom, talk with your doctor.
Here’s a closer look at certain drug interactions of Aptiom.
Birth control pills
Taking Aptiom with birth control pills can make the birth control less effective at preventing pregnancy.
Here are some birth control pills that may interact with Aptiom:
- desogestrel/ethinyl estradiol (Enskyce, Kariva)
- drospirenone/ethinyl estradiol (Loryna, Yaz)
- ethinyl estradiol/norethindrone (Junel, Balziva)
- levonorgestrel/ethinylestradiol (Seasonique, Falmina, Lessina)
Steps you or your doctor may take
If you take a birth control pill, your doctor will likely recommend switching to a different form of birth control that Aptiom does not affect. You can talk with your doctor about other methods that may be a good choice for you.
If you take Aptiom with a birth control pill, you should use an extra nonhormonal form of contraception, such as condoms, to help prevent pregnancy.
If you have questions about taking Aptiom with birth control pills, talk with your doctor or pharmacist.
Certain other seizure medications
Certain seizure medications can increase the action of enzymes in your body that help break down Aptiom. Taking Aptiom with one of these medications can make your body break down Aptiom faster than usual. This can lower the level of Aptiom in your body, which can make it less effective at treating seizures.
Here are some other seizure medications that may interact with Aptiom:
- carbamazepine (Tegretol, others)
- phenobarbital (Sezaby)
- phenytoin (Dilantin, Phenytek)
- primidone (Mysoline)
Steps you or your doctor may take
If you take Aptiom with one of these seizure medications, your doctor may prescribe a dosage of Aptiom that’s higher than usual.
If you have questions about taking Aptiom with other seizure medications, talk with your doctor or pharmacist.
Certain statins
Statins are a group of medications used to treat high cholesterol.
Aptiom can increase the action of an enzyme that helps break down certain statins called cytochrome p450 3A4 (CYP3A4). Taking Aptiom with one of these statins can make your body break down the statin faster than usual. This can lower the level of the statin in your body, which can make it less effective.
Here are some statins that may interact with Aptiom:
Steps you or your doctor may take
If your doctor prescribes Aptiom with a statin, they’ll likely check your cholesterol levels more often than usual. If the statin doesn’t seem to be working as well to lower your cholesterol, your doctor may increase your dosage of the statin.
If you have questions about taking Aptiom with a statin, talk with your doctor or pharmacist.
Aptiom may have other interactions, such as with supplements, foods, vaccines, or lab tests.
Here are some potential interactions with Aptiom. Keep in mind that the following information does not include all possible Aptiom interactions.
Aptiom and supplements
It’s possible for drugs to interact with supplements such as vitamins and herbs.
Aptiom and herbs
There are no specific reports of herbs interacting with Aptiom. However, that doesn’t mean herbal interactions won’t occur or be recognized in the future. Because of this, it’s important to check with your doctor or pharmacist before taking any of these products during Aptiom treatment.
Aptiom and vitamins
There are no specific reports of vitamins interacting with Aptiom. However, that doesn’t mean vitamin interactions won’t occur or be recognized in the future. Because of this, you should talk with your doctor or pharmacist before taking any vitamin product with Aptiom.
Aptiom and food
There were no reports of food interactions with Aptiom. If you’d like to learn more about eating certain foods during treatment with Aptiom, talk with your doctor.
Aptiom and vaccines
There are no known interactions between Aptiom and vaccines. Talk with your doctor or pharmacist to check whether you’re due for any vaccines.
Aptiom interactions with lab tests
Aptiom is not known to interact with lab tests. If you have concerns about this medication interacting with lab tests, talk with your doctor.
APTIOM INTERACTION WITH CANNABIS OR CBDCannabis (often called marijuana) and cannabis products, such as cannabidiol (CBD), have not been specifically reported to interact with Aptiom. However, Aptiom and cannabis can cause some similar side effects, such as drowsiness and dizziness. So if you use cannabis or cannabis products with Aptiom, you may have a raised risk of these side effects, or they may be worse.
As with any drug or supplement, talk with your doctor before using cannabis in combination with Aptiom. The impact of cannabis may also affect how well you stick to your Aptiom treatment plan.
Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.
Certain medical conditions and other factors may increase the risk of interactions with Aptiom. Before you take this drug, be sure to talk with your doctor about your health history. Aptiom may not be the right treatment option if you have certain medical conditions or other factors affecting your health.
Health conditions or factors that might interact with Aptiom include:
- Kidney problems: Your kidneys help remove Aptiom from your body. If you have a kidney problem, Aptiom can build up in your body. This can raise your risk of side effects, so your doctor may prescribe a dosage of Aptiom that’s lower than usual.
- Liver problems: Aptiom can sometimes cause liver problems. If you already have a liver problem, talk with your doctor about whether Aptiom is right for you.
- Mental health conditions: Aptiom can increase your risk of suicidal thoughts or actions. If you have a mental health condition or have a history of one, you may have a higher risk of this side effect. Talk with your doctor about whether Aptiom is right for you. If you take Aptiom, tell your doctor right away if you have any unusual changes in your mood, thoughts, or behavior.
- Allergic reaction: If you’ve had an allergic reaction to Aptiom or any of its ingredients or to a similar drug called oxcarbazepine (Trileptal), your doctor will likely not prescribe Aptiom. Taking the drug could cause another allergic reaction. You can ask them about other treatments that may be better choices for you.
- Breastfeeding: It is unknown whether it’s safe to use Aptiom while breastfeeding. The drug passes into breast milk, but it is unknown what effects Aptiom may have on a child who is breastfed. If you’re breastfeeding or planning to, talk with your doctor before using Aptiom. They can talk with you about treatment options and ways to feed a child other than breastfeeding.
- Pregnancy: There haven’t been enough clinical trials to determine whether Aptiom is safe to use while pregnant. Animal studies show that the drug may cause congenital anomalies (commonly known as birth defects) or pregnancy loss. However, it’s important to note that animal studies don’t always indicate what may happen in humans. If you’re pregnant or planning to become pregnant, tell your doctor before starting Aptiom. They can advise you on the right treatment plan for you.
Help is out there
If you or someone you know is in crisis and considering suicide or self-harm, please seek support:
- Call or text the 988 Lifeline at 988 or chat at 988lifeline.org. Caring counselors are available to listen and provide free and confidential support 24/7.
- Text HOME to the Crisis Text Line at 741741 to connect with a volunteer crisis counselor for free and confidential support 24/7.
- Not in the United States? Find a helpline in your country with Befrienders Worldwide.
- Call 911 or your local emergency services number if you feel safe to do so.
If you’re calling on behalf of someone else, stay with them until help arrives. You may remove weapons or substances that can cause harm if you can do so safely.
If you’re not in the same household, stay on the phone with them until help arrives.
You can take certain steps to help prevent interactions with Aptiom. Your doctor and pharmacist are key resources, so reaching out to them before starting treatment is a helpful first step. For example, it’s important that you plan to do the following:
- Let them know if you drink alcohol or use cannabis.
- Tell them about any other medications you take, as well as any supplements, herbs, and vitamins.
- Create a
medication listTrusted Source , which your doctor and pharmacist can help you fill out.
It’s also important to read the Aptiom label and other
If Aptiom doesn’t come with paperwork, you can ask your pharmacist to print a copy. If you need help reading or understanding this information, ask your doctor or pharmacist.
You can also help prevent interactions with Aptiom by taking it exactly as your doctor prescribes.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.