NovoSeven RT (coagulation factor VIIa, recombinant) may be unsafe to use while pregnant or breastfeeding. Certain factors, including the risks of not treating your condition during pregnancy or breastfeeding, may determine whether you should use the drug during this time.
Boxed warning: Risk of blood clots
This drug has a boxed warning about the risk of blood clots. A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.
NovoSeven RT infusions could increase the risk of blood clots, which may be fatal in certain cases. These clots may occur in a lung or a deep vein. Blood clots may lead to heart attack or stroke.
Symptoms can vary depending on where the clot occurs. Examples include difficulty breathing, chest pain, and warmth, pain, or swelling in the affected area.
Having heart or blood vessel disease may increase the risk of blood clots when using NovoSeven RT. This risk may also be greater if NovoSeven RT is used with other medications, such as anti-inhibitor coagulant complex (Feiba) or coagulation factor XIII (Corifact, Tretten). These interactions are described in the article below. (“Coagulation” is another term for blood clotting, and a coagulant is a substance that helps blood clot.)
If you have symptoms of a blood clot during treatment with NovoSeven RT, contact your doctor right away. But if your symptoms seem severe or life threatening, call 911 or a local emergency number.
For more information on this warning, talk with your doctor or pharmacist.
Show MoreIf you may be or can become pregnant, it is important to consider whether NovoSeven RT is safe for you.
It is unknown whether NovoSeven RT should be used during pregnancy. If you are planning a pregnancy or can become pregnant, talk with your doctor before starting this medication.
NovoSeven RT is used to treat multiple conditions, including:
- hemophilia A or B
- acquired hemophilia
- congenital (present from birth) clotting factor VII deficiency (clotting factors are proteins that help the blood clot) in certain people
It is important to note that not treating your diagnosed condition during pregnancy may also carry certain risks.
Because of this, you and your doctor need to discuss the risks and benefits of taking NovoSeven RT while pregnant versus not treating your condition during pregnancy.
If you are currently breastfeeding or planning to do so, it is important to understand the effects that NovoSeven RT could have on you or the breastfed child.
It is unknown whether NovoSeven RT should be used while breastfeeding. If you are currently breastfeeding or planning to do so, talk with your doctor before using or receiving this medication.
If you are sexually active and you or your partner can become pregnant, it is important to consider how NovoSeven RT could affect your birth control options.
It is not known whether NovoSeven RT is safe for use during pregnancy. If you are sexually active and you or your partner can become pregnant, consult a doctor about your birth control needs during NovoSeven RT treatment.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
