Nurtec ODT (rimegepant) is a brand-name drug prescribed for treating and preventing migraine in adults. Nurtec ODT comes as a tablet that dissolves in your mouth. The dosage can vary depending on whether you are using it to treat or prevent migraine.
Nurtec ODT is approved by the Food and Drug Administration (FDA) to:
- treat migraine episodes that occur with or without aura in adults
- help prevent episodic migraine in adults
Nurtec ODT belongs to a class of drugs called calcitonin gene-related peptide (CGRP) receptor antagonists. There is no generic form of Nurtec ODT at this time.
Keep reading for specific information about the dosage of Nurtec ODT, including its strength and how to take the medication. For more comprehensive details about this medication, see this overview article on Nurtec ODT.
Read on for important information about Nurtec ODT dosage for its approved uses.
Nurtec ODT form
Nurtec ODT is an orally disintegrating tablet. This means it dissolves when placed in your mouth or under your tongue.
Nurtec ODT strength
Nurtec ODT comes in one strength: 75 milligrams (mg).
Typical dosages
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.
Dosage for acute migraine treatment
The following table shows the typical dosage schedule for treating acute (immediate) migraine, with or without aura, including the recommended and maximum dosages.
| Purpose | Recommended dosage | Maximum dosage | Maximum doses in a 30-day period |
| acute treatment of migraine | 75 mg once per day, as needed | 75 mg every 24 hour | 18 doses |
The typical dosage of Nurtec ODT for acute migraine treatment is 75 mg once per day, as needed. This means you only take Nurtec ODT when you have a migraine episode.
For more information about your specific dosage for treating migraine, talk with your doctor.
Dosage for migraine prevention
The following table highlights the typical dosage schedule for preventing episodic migraine, including the recommended and maximum dosages.
| Purpose | Recommended dosage | Maximum dosage | Maximum doses in a 30-day period |
| prevention of episodic migraine | 75 mg every other day | 75 mg in 24 hours | unknown |
Nurtec ODT’s recommended dosing for preventing episodic migraine is 75 mg every other day. In this case, you will take Nurtec ODT on a schedule (every other day).
For more information about your specific dosage for preventing migraine, talk with your doctor.
Long-term treatment
Nurtec ODT is meant to be used as needed to treat acute migraine attacks. This means you may use it as needed over a long period.
To prevent episodic migraine, you may use Nurtec ODT on a long-term schedule.
If you and your doctor determine that Nurtec ODT is safe and effective for you, you’ll likely take it long term since migraine can be a chronic condition.
The Nurtec ODT dosage your doctor prescribes will depend on several factors. These include:
- the type and severity of the condition you’re using Nurtec ODT to treat
- other drugs you’re taking
- other medical conditions you have
- how well your kidneys and liver function
Dosage adjustments
Your doctor may need to adjust your dosage if you take other medications in combination with Nurtec ODT. Some drugs may cause you to have too much or too little Nurtec ODT in your body.
Certain medications that affect enzymes in the body can interact with Nurtec ODT. These drugs are known as CYP3A4 inhibitors and CYP3A inducers. Examples of CYP3A4 inhibitors include Nizoral (ketoconazole) and Verelan (verapamil). And examples of CYP3A inducers include Rifadin (rifampin) or Dilantin (phenytoin).
Drugs that affect P-glycoprotein can also increase levels of Nurtec ODT in your body. These drugs include Noxafil (posaconazole) and propafenone.
Tell your doctor about all of the medications you take before starting treatment with Nurtec ODT. They may adjust how often you take the drug.
Nurtec ODT comes as an orally disintegrating tablet. You can take this tablet by letting it dissolve on or under your tongue. Let the tablet dissolve fully, and then swallow it without water. You should avoid eating or drinking until you’ve swallowed the dissolved tablet. Do not crush, split, or chew Nurtec ODT tablets.
To treat an acute migraine attack, take Nurtec ODT as soon as you have symptoms of migraine or aura. To prevent episodic migraine, take Nurtec ODT every other day or as your doctor prescribes.
Accessible drug labels and containersIf you’re having trouble reading your prescription label, talk with your doctor or pharmacist. Some pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.
If you’re having trouble opening medication bottles, ask your pharmacist about putting Nurtec ODT in an easy-open container. They may also recommend tools that can make it easier to open bottles.
If you miss a Nurtec ODT dose for prevention of episodic migraine and have questions about what to do, talk with your doctor or pharmacist.
To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or using a timer. You could also download a reminder app on your phone.
It is important that you do not use more Nurtec ODT than your doctor prescribes. Taking more than the recommended amount of some medications may lead to side effects or overdose.
If you take more than the recommended amount of Nurtec ODT
Call your doctor right away if you believe you’ve taken too much Nurtec ODT. Another option is to call America’s Poison Centers at 800-222-1222 or use its online tool. If you have severe symptoms, immediately call 911 or your local emergency number, or go to the nearest emergency room.
Besides learning about the dosage of Nurtec ODT, you may want other information about this medication or migraine treatment or prevention. These articles may be helpful:
- More about Nurtec ODT. For more information about other aspects of Nurtec ODT, refer to this Nurtec ODT overview article.
- Side effects. Learn more about the side effects of Nurtec ODT. You can also refer to the Nurtec ODT prescribing information.
- Details about migraine. For more details about migraine, our headache and migraine hub might be helpful, as well as these related migraine articles.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
