Zeposia (ozanimod) is not safe to take while pregnant or breastfeeding. Certain factors, including the risks of fetal harm, may determine whether you can take the drug during this time.
If you may be or can become pregnant, it’s important to consider whether Zeposia is a safe option for you.
It’s a good idea to avoid taking Zeposia during pregnancy. If you’re planning a pregnancy or can become pregnant, talk with your doctor before taking this medication. Your doctor may suggest birth control options to use during treatment with Zeposia. Also, avoid becoming pregnant until at least 3 months after stopping Zeposia treatment.
If you become pregnant while taking Zeposia for multiple sclerosis (MS), consider taking part in the drug’s MS pregnancy registry. A pregnancy registry helps gather information on how certain drugs can affect pregnancy. To learn more, call 877-301-9314, visit the registry site, or talk with your doctor.
Your doctor can tell you whether there’s a pregnancy registry for people taking Zeposia for ulcerative colitis during pregnancy.
If you’re currently breastfeeding or planning to do so, it’s important to understand the effects that Zeposia could have on you or the breastfed child.
It’s not known whether you can take Zeposia while breastfeeding. There’s no information on whether ozanimod (Zeposia’s active ingredient) passes into breast milk or what effects the drug may have on a breastfed child. However, a 2022 research review recommended against breastfeeding during Zeposia treatment.
If you’re currently breastfeeding or planning to do so, talk with your doctor before taking this medication.
If you’re sexually active and you or your partner can become pregnant, it’s important to consider how Zeposia could affect your birth control options.
Note: In this article, we use the terms “females” and “males” to refer to someone’s sex assigned at birth. For information, see this article about the difference between sex and gender.
For females taking Zeposia
If you can become pregnant, use birth control while taking Zeposia and for at least 3 months after your last dose.
For males taking Zeposia
The manufacturer of Zeposia doesn’t provide birth control recommendations for males. If you have a sexual partner who can become pregnant, ask your doctor for birth control recommendations while you’re taking Zeposia.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
